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Radical scavenger and antihepatotoxic activity of Ganoderma formosanum,...

The free radical scavenging and antihepatotoxic activity from Ganoderma lucidum, Ganoderma formosanum and Ganoderma neo-japonicum were studied. Treatment with the water extract of Ganoderma lucidum, Ganoderma formosanum and Ganoderma neo-japonicum caused a...
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An immunomodulating protein, Ling Zhi-8 (LZ-8) prevents insulitis in non-...

Ling Zhi-8 (LZ-8), a novel and recently discovered immunomodulatory protein having in vivo immuno-suppressive activity, was tested for in vivo effect against Type 1 (insulin-dependent) diabetes mellitus in the nonobese diabetic mouse, the disease having...
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Cytotoxicity and immunogenicity of SACCHACHITIN and its mechanism of...

SACCHACHITIN membrane, a weavable skin substitute made from the residual fruiting body of Ganoderma tsugae, has been demonstrated to promote skin wound healing. Prior to its clinical application, it is critical to learn more about any possible cytotoxicity,...
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Development of fungal mycelia as skin substitutes: effects on wound...

In this study, Sacchachitin membrane, prepared from the residue of the fruiting body of Ganoderma tsugae, was estimated for its effects on wound healing and the proliferation and migration of fibroblast cells. Two mirror-image wounds were made on the back of...
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Psychoneuroimmunological effects of morphine and the immunoprotection of...

Different kinds of single, multiple, acute or chronic administrations of morphinized animal models were established, with which a series of experiments in both in vivo and in vitro systems as well as molecular levels were pharmacologically designed to...
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An experimental study on the effects of lingzhi spore on the immune...

Lingzhi spore (2 g.kg-1.d-1, 10 times) was orally administered to mice, and studies were carried out on the carbon clearance, delayed-type skin hypersensitivity (DTH), antibody hemagglutinin value and spleen weight. The results showed that Lingzhi spore could...
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Isolation and characterization of a new immunomodulatory protein, ling zhi...

A novel protein with mitogenic activity in vitro and immunomodulating activity in vivo has been isolated from the mycelial extract of an Oriental medicinal fungus, ling zhi (Ganoderma lucidium). This protein was named ling zhi-8 (LZ-8) and its biochemical and...
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Complete amino acid sequence of an immunomodulatory protein, ling zhi-8 (...

The complete amino acid sequence of a novel immunomodulatory protein, ling zhi-8 (LZ-8), isolated from a fungus, Ganoderma lucidium (Kino, K., Yamashita, A., Yamaoka, K., Watanabe, J., Tanaka, S., Ko, K., Shimizu, K., and Tsunoo, H. (1989) J. Biol. Chem. 264...
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Chemical studies on immunologically active polysaccharides of Ganoderma...

BN3B, the polysaccharide component of the fruit of Ganoderma lucidum, has been shown to have immune activity. From BN3B four homogeneous polysaccharides were separated and purified. Chemical studies on the main components BN3B1 and BN3B3 indicated that BM3B1...
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Anti-atherosclerotic properties of higher mushrooms (a clinico-...

Antiatherosclerotic properties of water and alcoholic extracts of 20 types of high-species mushrooms were investigated by evaluation of intracellular cholesterol accumulation and 3H-thymidine inclusion into the cells of the human aortal intima in culture. The...
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